Caractéristiques principales
- StemRegenin1 (SR1) is an antagonist of the aryl hydrocarbon receptor (AHR)
- It promotes ex vivo expansion of CD34+ human hematopoietic stem cells (Boitano et al.), 2010, Csazar et al.), 2012)
- SR1 has been shown to collaborate with UM729 in preventing differentiation of acute myeloid leukemia (AML) cells in culture (Pabst et al.), 2014)
- SR1 also stimulates the proliferation and differentiation of CD34+ hematopoietic progenitor cells into dendritic cells (Thordardottir et al.), 2014)
- This product is supplied as the hydrochloride salt of the molecule
Caractéristiques techniques
| Marque | STEMCELL Technologies |
| Réf. B-LABO | BL-RE-126495 |
| Réf. fabricant | 17119251 |
| Synonyme | SR1 (Hydrochloride) |
|---|
| Quantité | 1 mg |
|---|
| Formule moléculaire | C<sub>24</sub>H<sub>23</sub>N<sub>5</sub>OS · HCl |
|---|
| Pureté | ≥98% |
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