Cardiogenol C is a diaminopyrimidine that induces cardiomyogenesis in mouse embryonic stem cells
Its use results in expression of GATA-4, MEF2, and Nkx2.5
Induces trans-differentiation of mouse CD34+K15+ hair bulge progenitor cells into cardiomyocyte-like cells (Yau et al.)
Induces cardiomyogenic function in the lineage-committed progenitor cells, C2C12 skeletal myoblasts and mouse A5 cardiovascular progenitor cells (Mike et al.)
Induces the differentiation of myosin heavy chain (MHC)-positive cardiomyocytes from mouse embryonic stem cells (Wu et al.)
