Inhibitor of NME2 localization; Suppresses c-MYC expression
CAS
154589-96-5
Synonyme
N-Benzoyl-7-oxo Staurosporine
Quantité
1 mg
Formule moléculaire
C35H28N4O5
Pureté
≥98%
Marque
STEMCELL Technologies
Caractéristiques principales
Stauprimide specifically inhibits the nuclear localization of NME2, which results in the suppression of c-MYC—a key regulator of pluripotency—thereby priming cells for differentiation (Zhu et al.)
Enhances cytokine-mediated directed differentiation of mouse and human pluripotent stem cells to multiple lineages, including definitive endoderm, neural progenitors, and mesodermal derivatives such as cardiomyocytes (Zhu et al.; Tahamtani et al.)