Butein is a plant polyphenol, tetrahydroxychalcone that inhibits nuclear factor (NF)-κB (Yang et al; Pandey et al. 2007)
Butein has been shown to prevent phosphorylation and degradation of TNF-dependent IκBα, an inhibitory subunit of NF-κB (IC50 = 38 μM; Orlikova et al.) Butein also inhibits 5-lipoxygenase (IC50 = 0.01 μM; Sogawa et al.), the enoyl-acyl-carrier protein reductase of Plasmodium falciparum (Ki = 2.97 μM; Sharma et al.), angiotensin-converting enzyme (IC50 = 0.73 mM; Bonesi et al.), and SRC kinase (Pandey et al. 2009)
Caractéristiques techniques
Marque
STEMCELL Technologies
Réf. B-LABO
BL-RE-126726
Réf. fabricant
17190222
CAS
487-52-5
Synonyme
2',3,4,4'-Tetrahydroxychalcone
Quantité
1 mg
Formule moléculaire
C<sub>15</sub>H<sub>12</sub>O<sub>5</sub>
Pureté
≥95%
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