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STEMCELL Technologies CHIR98014 | B-LABO France
STEMCELL Technologies CHIR98014
Réf. : BL-RE-126735Réf. fabricant : 17150162 1 mg
153,90 € HT
WNT pathway activator; Inhibits GSK3α and GSK3β
CAS
556813-39-9
Quantité
1 mg
Formule moléculaire
C20H17Cl2N9O2
Pureté
≥98%
Marque
STEMCELL Technologies
Caractéristiques principales
CHIR98014 is a reversible, cell-permeable activator of the WNT pathway, through inhibition of both isoforms of glycogen synthase kinase 3 (GSK3α and GSK3β) with IC50 values of 0.65 and 0.58 nM, respectively
It shows at least 500-fold selectivity for GSK-3 versus 20 other serine/threonine or tyrosine kinases (Ring et al.)
