TRPC5 inhibitor
AM 12 is a TRPC5 inhibitor (IC50 = 0.28 μM); Galangin (Cat. No. 6494) derivative. Exhibits some selectivity for TRPC5 over TRPC2, 3 and 4. Inhibits effects of TRPC5 activator (-)-Englerin A, but potentiates effects of physiological activators Sphingosine-1-phosphate (Cat. No.1370) and LPC.
| Marque | Tocris |
|---|---|
| Réf. B-LABO | BL-RE-126788 |
| Réf. fabricant | 18765956 |
| Quantité | 10 mg |
| Formule moléculaire | C<sub>15</sub>H<sub>9</sub>BrO<sub>5</sub> |
| Poids de la formule | 349.14 |
| Type de produit | Inhibitor |
| Pureté | 97% |
