High affinity A1 receptor agonist
N6
-Cyclohexyladenosine is a high affinity adenosine A1 receptor agonist (Kd values are 0.7 and 6 nM for bovine and guinea pig brain membranes, respectively). Reduces light-induced circadian phase delays. Exhibits protective effect in lysolecithin-induced demyelination model. When administered prior to ischemia, improves functional recovery of heart in a mouse model of ischemia-reperfusion injury. Induces hypothermia following icv administration in mice.
| Marque | Tocris Bioscience |
|---|---|
| Réf. B-LABO | BL-RE-126805 |
| Réf. fabricant | 18798706 |
| Nom chimique ou matériau | N-Cyclohexyladenosine |
| CAS | 36396-99-3 |
| Quantité | 50 mg |
| Formule moléculaire | C<sub>16</sub>H<sub>23</sub>N<sub>5</sub>O<sub>4</sub> |
| Pureté | 98% |
