Use these columns in small-scale MAb purification in a continuous bioprocess. Cytiva Life Sciences™ HiTrap™ MabSelect™ Prepacked Columns for fast purification of monoclonal antibodies (Mabs) from large sample volumes
Type de produit
Pre-packed Columns
Capacité de liaison
∼30 mg/mL Human lgG at 2.4 min. residence time
Diamètre (métrique) de la colonne intérieure
0.7 cm
Diamètre (impériale) de la colonne intérieure
0.27 in.
Débit
<4 mL/min.
Marque
Cytiva
Prepacked HiTrap columns for process development, screening of purification conditions, and small-scale purification of Mabs. MabSelect media are suited for the high flowrates and pressures required when scaling up.
Points forts
MabSelect
Allows at least five times higher flowrates than conventional cross-linked agarose of similar porosity
Recombinant Protein A ligand promotes specificity of binding to Fc region of IgG; permits one-step purification
MabSelect Xtra™
Same recombinant protein A ligand as MabSelect, but with a smaller particle size and greater porosity, for increased dynamic binding capacity
Allows binding from samples with high expression levels of the monoclonal antibody
Lowers overall production cost due to the possibility of processing concentrated feedstocks in fewer batches
MabSelect SuRe™ (Superior Resistance)
Akali-tolerant protein A-derived ligand allows the use of up to 0.5M NaOH for cleaning-in-place (CIP)
Permits significant cost savings and extension of cycles in regular production
Caractéristiques principales
Oriented coupling of recombinant Protein A ligand to the agarose matrix via an engineered C-terminal cysteine increases IgG binding capacity over other protein A media
High capacity, low ligand leakage, and high-flow base matrix allow purification of Mabs at process scale
Fewer regulatory concerns due to the total absence of mammalian culture in the ligand production and purification
Designed for use with a syringe, a peristaltic pump, or a chromatography system
Caractéristiques techniques
Marque
Cytiva
Réf. B-LABO
BL-RE-126892
Réf. fabricant
10359534
Type de produit
Pre-packed Columns
Capacité de liaison
∼30 mg/mL Human lgG at 2.4 min. residence time
Diamètre (métrique) de la colonne intérieure
0.7 cm
Diamètre (impériale) de la colonne intérieure
0.27 in.
Débit
<4 mL/min.
Volume (métrique) du lit
1 mL
À utiliser avec (application)
For fast purification of monoclonal antibodies from large sample volumes, Protein Purification
Volume d’échantillon
1 mL
Tampon de stockage
20% Ethanol
Contenu et stockage
4°C to 30°C
Quantité
5 Pk.
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