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Thermo Scientific™ CaptureSelect™ FcXP Affinity Matrix

Réf. : BL-RE-127463Réf. fabricant : 18486398 10 mL
1 596,00 € HT

CaptureSelect FcXP Affinity Matrix is the next-generation CaptureSelect FcXL matrix, specifically designed for higher binding capacity.

Capacité de liaison
40 to 50 g IgG/L resin
Débit
50 to 200 cm/hr. (Up to 2 bar)
Matrice
Agarose-based, epoxide activated
Granulométrie
65 ± 10 μm
Forme
Resin Slurry
Marque
Thermo Scientific

Features of this affinity matrix include:

CaptureSelect FcXP Affinity Matrix can be used for the purification of IgG and Fc fusion proteins directly from complex source materials and enables a robust and efficient purification process with excellent purity obtained in one step.

Points forts

Free of animal components

CaptureSelect products contain affinity ligands based on recombinant single-domain antibody fragments (VHH) created by a proprietary technology. The VHH affinity ligand is a 12 to 15 kDa fragment comprising the three complementarity-determining regions (CDRs) that form the antigen-binding domain, efficiently produced in the yeast Saccharomyces cerevisiae by a production process free of any animal components (Animal Origin-Free).

Main characteristics

  • Matrix: agarose-based, epoxide activated
  • Average particle size: 65 ± 10 μm
  • Ligand: CaptureSelect FcXP affinity ligand
  • Ligand coupling method: epoxide coupling
  • Binding capacity: 40–50 g IgG/L resin depending on flow rate, column height, and contact time
  • Elution conditions: 20 mM citric acid or acetic acid, pH 3–4, or 100 mM Tris, 2.0 M MgCl2, 40% (v/v) propylene glycol, pH 7

Caractéristiques principales

  • Mild elution, making it suitable for Fc fusion proteins
  • Human-specific, no binding to bovine antibodies
  • Excellent scalability
  • Non-animal derived

Caractéristiques techniques

MarqueThermo Scientific
Réf. B-LABOBL-RE-127463
Réf. fabricant18486398
Capacité de liaison40 to 50 g IgG/L resin
Débit50 to 200 cm/hr. (Up to 2 bar)
MatriceAgarose-based, epoxide activated
Granulométrie65 ± 10 μm
FormeResin Slurry
Gamme de produitsCaptureSelect™
Quantité10 mL
TypeAffinity Matrix
Type de ligandFcXP affinity ligand
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