Réf. : BL-RE-127496Réf. fabricant : 18406688 50 mL
Prix sur devis
Tarif personnalisé selon la configuration et la quantité.
POROS CaptureSelect AAVX Affinity Resin is engineered to address the high selectivity and capacity requirements for large-scale downstream purification of a broad range of naturally occurring and synthetic adeno-associated virus (AAV) serotypes used for gene therapy applications.
Features of POROS CaptureSelect AAVX resin include:
POROS CaptureSelect AAVX Affinity Resin enables a robust, fast, and platformable purification process for wide-ranging AAV serotypes with excellent purity and yield obtained in one step. This resin comes with complete technical and regulatory support.
Points forts
Main characteristics
Matrix: cross-linked poly(styrene-divinylbenzene) POROS beads
Average particle size: 50 μm
Ligand: CaptureSelect AAVX affinity ligand
Binding capacity: >1 x 1013 genome copies/mL of resin
Elution conditions: acidic elution with 0.1 M glycine, pH 3.0
Mechanical resistance: 100 bar (1450 psi; 10 MPa)
Free of animal components
CaptureSelect products contain affinity ligands based on recombinant single-domain antibody fragments (VHH) created by a proprietary technology. The VHH affinity ligand is a 12 to 15 kDa fragment comprising the three complementarity-determining regions (CDRs) that form the antigen-binding domain, efficiently produced in the yeast Saccharomyces cerevisiae by a production process free of any animal components (Animal Origin-Free).
Caractéristiques principales
One-step AAV purification from crude material with high purity and yield
High specificity and capacity, maximizing yield by significantly reducing process steps
Superior capacity maintained at high flow rates
Excellent scalability and easier handling and packing due to rigid polymeric bead
Non-animal derived
Caractéristiques techniques
Marque
Thermo Scientific
Réf. B-LABO
BL-RE-127496
Réf. fabricant
18406688
Capacité de liaison
>1 x 10<sup>13</sup> genome copies/mL of resin
Contenu et stockage
Store in refrigerator at 2°C to 8°C.
Conditions d’expédition
Wet Ice
Granulométrie
50 μm
Forme
Liquid Suspension
Gamme de produits
POROS™
Quantité
50 mL
Type
Resin
Type de colonne
Affinity
Une question, une configuration particulière ? Contactez-nous pour un devis.
