POROS CaptureSelect AdV5 Affinity Matrix was designed specifically for the purification and/or scavenging of recombinant hexon capsomeres of Adenovirus serotype 5 (AdV5) particles, as well as free hexon proteins thereof, for high purity in a single step.
Capacité de liaison
>1 x 1011 genome copies/mL of resin
Matrice
Cross-linked poly(styrene-divinylbenzene)
Contenu et stockage
Store in refrigerator (2°C to 8°C).
Conditions d’expédition
Approved for shipment at Room Temperature or on Wet Ice
Granulométrie
50 μm
Marque
Thermo Scientific
Features of this affinity matrix include:
Points forts
Free of animal components
CaptureSelect products contain affinity ligands based on recombinant single-domain antibody fragments (VHH) created by a proprietary technology. The VHH affinity ligand is a 12 to 15 kDa fragment comprising the three complementarity-determining regions (CDRs) that form the antigen-binding domain, efficiently produced in the yeast Saccharomyces cerevisiae by a production process free of any animal components (Animal Origin-Free).
Main characteristics
Matrix: cross-linked poly(styrene-divinylbenzene)
Average particle size: 50 μm
Ligand: CaptureSelect AdV5 affinity ligand
Ligand coupling method: epoxide
Binding capacity: >1 x 1011 genome copies/mL of resin
Elution conditions: acidic elution with 0.1 M glycine, pH 3.0
Caractéristiques principales
One-step purification of virus particles from crude material with high purity and yield
High specificity, capacity, and retained activity
Excellent scalability
Non-animal derived
High flow rates
Caractéristiques techniques
Marque
Thermo Scientific
Réf. B-LABO
BL-RE-127572
Réf. fabricant
18456448
Capacité de liaison
>1 x 10<sup>11</sup> genome copies/mL of resin
Matrice
Cross-linked poly(styrene-divinylbenzene)
Contenu et stockage
Store in refrigerator (2°C to 8°C).
Conditions d’expédition
Approved for shipment at Room Temperature or on Wet Ice
Granulométrie
50 μm
Forme
Liquid Suspension
Gamme de produits
CaptureSelect™, POROS™
Quantité
5 mL
Type
Affinity Matrix
Type de ligand
AdV5 affinity ligand
Phase stationnaire
AdV5
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