CaptureSelect KappaXP Affinity Matrix is the improved version of CaptureSelect KappaXL Affinity Matrix, with a significant increase in binding capacity for both whole kappa monoclonal antibodies and kappa Fab's.
Débit
150 to 300 cm/hr. (Up to 2 bar)
Matrice
Agarose-based
Contenu et stockage
Store in refrigerator (2°C to 8°C).
Conditions d’expédition
Wet Ice
Granulométrie
65 ± 10 μm
Marque
Thermo Scientific
CaptureSelect KappaXP matrix recognizes the kappa light chain of human antibodies, enabling purification of all kappa-containing Ig's, Fab, and Fab2 fragments directly from complex sources and feed streams.
CaptureSelect KappaXP Affinity Matrix features include:
The high selectivity and high yields obtained using CaptureSelect KappaXP Affinity Matrix enable a robust and efficient purification process with excellent purity in one step.
Points forts
Free of animal components
CaptureSelect products contain affinity ligands based on recombinant single-domain antibody fragments (VHH) created by a proprietary technology. The VHH affinity ligand is a 12 to 15 kDa fragment comprising the three complementarity-determining regions (CDRs) that form the antigen-binding domain, efficiently produced in the yeast Saccharomyces cerevisiae by a production process free of any animal components (Animal Origin-Free).
Main characteristics
Matrix: agarose-based
Average particle size: 65 ± 10 μm
Ligand: CaptureSelect KappaXP affinity ligand
Ligand coupling method: epoxide immobilization of the ligand
Fab binding capacity: 20–30 g IgG Kappa-Fab/liter resin depending on flow rate, column height, and residence time
IgG binding capacity: 35–45 g IgG/liter resin depending on flow rate, column height, and residence time
Caractéristiques principales
Purification of kappa monoclonal antibodies, Fab, and Fab2 fragments directly from complex source materials in a single step with high purity and yield
Mild elution for Fab fragments and antibodies
Human specific, no binding to bovine antibodies
Excellent scalability
Excellent pH stability up to 100 mM NaOH for limited exposure
Non–animal-derived
Caractéristiques techniques
Marque
Thermo Scientific
Réf. B-LABO
BL-RE-127631
Réf. fabricant
18406698
Débit
150 to 300 cm/hr. (Up to 2 bar)
Matrice
Agarose-based
Contenu et stockage
Store in refrigerator (2°C to 8°C).
Conditions d’expédition
Wet Ice
Granulométrie
65 ± 10 μm
Forme
Agarose Bead
Gamme de produits
CaptureSelect™
Quantité
5 mL
Type
Affinity Matrix
Type de ligand
KappaXP affinity ligand
Phase stationnaire
KappaXP
Une question, une configuration particulière ? Contactez-nous pour un devis.
