CaptureSelect FcXP MiniChrom columns are designed for bench-scale resin screening, process development, and sample preparation.
The 1-mL columns can be used for quick screenings of application feasibility and lab scale purification on a convenient and easy-to-use pre-packed column. The 10-cm bed height of the 5-mL columns allows initial process development on a bench scale.
CaptureSelect FcXP Affinity Matrix recognizes the CH3 domain of all human IgG subclasses (IgG1, 2, 3, and 4), enabling purification of all IgG subclasses and Fc fusion proteins directly from complex source materials in a robust and efficient purification process with excellent purity obtained in a single step.
Features of the FcXP affinity matrix include:
CaptureSelect products contain affinity ligands based on recombinant single-domain antibody fragments (VHH) created by a proprietary technology. The VHH affinity ligand is a 12 to 15 kDa fragment comprising the three complementarity-determining regions (CDRs) that form the antigen-binding domain, efficiently produced in the yeast Saccharomyces cerevisiae by a production process free of any animal components (Animal Origin-Free).
| Marque | Thermo Scientific |
|---|---|
| Réf. B-LABO | BL-RE-127705 |
| Réf. fabricant | 18416618 |
| Capacité de liaison | 40 to 50 g IgG/L resin |
| Capacité (métrique) | 1 mL |
| Débit | 75 to 150 cm/hr. (Up to 2 bar) |
| Matrice | Agarose-based, epoxide-activated |
| Diamètre (métrique) | 0.8 cm |
| Longueur (métrique) | 2 cm |
| Granulométrie | 65 ± 10 μm |
| Gamme de produits | CaptureSelect™ |
| Quantité | 1 Column |
| Type | Pre-packed Column |
| Type de ligand | FcXP affinity ligand |
| Type de colonne | MiniChrom |
