CaptureSelect AAT-XL Affinity Matrix has been specifically designed for the purification of native human alpha-1 antitrypsin (AAT) from complex sources like plasma/serum and recombinant human AAT from cell culture supernatants.
Capacité de liaison
15 mg AAT/mL resin
Débit
50 to 200 cm/hr. (Up to 2 bar)
Matrice
Agarose-based, epoxide-activated
Granulométrie
65 ± 10 μm
Forme
Resin Slurry
Marque
Thermo Scientific
Features of this affinity matrix include:
Points forts
Free of animal components
CaptureSelect products contain affinity ligands based on recombinant single-domain antibody fragments (VHH) created by a proprietary technology. The VHH affinity ligand is a 12 to 15 kDa fragment comprising the three complementarity-determining regions (CDRs) that form the antigen-binding domain, efficiently produced in the yeast Saccharomyces cerevisiae by a production process free of any animal components (Animal Origin-Free).
Main characteristics
Matrix: agarose-based, epoxide-activated
Average particle size: 65 ± 10 μm
Ligand: CaptureSelect AAT-XL affinity ligand
Ligand coupling method: epoxide coupling
Binding capacity: 15 mg AAT/mL resin
Elution conditions: 20 mM Tris, 2.0 M MgCl2, pH 6.0
Caractéristiques principales
Highly selective for native and recombinant human AAT
High recovery and yield obtained in a single purification step
Mild elution at pH 6
Excellent scalability
Non-animal-derived
Caractéristiques techniques
Marque
Thermo Scientific
Réf. B-LABO
BL-RE-127856
Réf. fabricant
18486508
Capacité de liaison
15 mg AAT/mL resin
Débit
50 to 200 cm/hr. (Up to 2 bar)
Matrice
Agarose-based, epoxide-activated
Granulométrie
65 ± 10 μm
Forme
Resin Slurry
Gamme de produits
CaptureSelect™
Quantité
5 mL
Type
Affinity Matrix
Type de ligand
AAT-XL affinity ligand
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