"/> Cytiva™ MabSelect™ VL Protein L Resin | B-LABO France

Cytiva™ MabSelect™ VL Protein L Resin

Réf. : BL-RE-128241Réf. fabricant : 17827774
1 425,00 € HT

The MabSelect™ VL resin is a protein L resin for affinity capture of antibody Fabs, bispecifics, and other variants containing a kappa light chain.

Volume du lit
25 mL
Débit
300 cm/hr.
Type de ligand
Alkaline Stabilized Protein L-derived (E. coli)
Plage de pH
2 to 10
Granulométrie
60 μm
Marque
Cytiva

MabSelect™ VL resin with a redesigned protein L ligand for high binding capacity and improved alkaline stability. For affinity capture of antibody Fabs, bispecifics, and other variants containing a kappa light chain.

As the diversity of antibody variants increases, so does the need for chromatography resins that can capture and purify these variants. As an alternative to protein A, protein L resin can be used to capture antibody Fabs, bispecific antibodies, and other molecules containing kappa variants of the variable light (VL) chain. Protein L binds human kappa light chain subtypes 1, 3, and 4 and mouse kappa light chain subtype 1.

Caractéristiques principales

  • High dynamic binding capacity protein L resin for efficient capture of antibody Fabs, bispecifics, and variants containing a kappa light chain
  • Stable when cleaned with 0.1 M NaOH, reducing risk for bioburden incidents
  • Provides good resolution for product-related impurities in the capture of bispecific antibodies

Caractéristiques techniques

MarqueCytiva
Réf. B-LABOBL-RE-128241
Réf. fabricant17827774
Volume du lit25 mL
Débit300 cm/hr.
Type de ligandAlkaline Stabilized Protein L-derived (E. coli)
Plage de pH2 to 10
Granulométrie60 μm
Contenu et stockage2°C to 8°C, 20% Ethanol
À utiliser avec (application)Antibody Affinity Chromatography
dimMatrixVL Protein L Resin
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