Cytiva™ MabSelect™ VL Protein L Resin | B-LABO France
Cytiva™ MabSelect™ VL Protein L Resin
Réf. : BL-RE-128241Réf. fabricant : 17827774
1 425,00 € HT
The MabSelect™ VL resin is a protein L resin for affinity capture of antibody Fabs, bispecifics, and other variants containing a kappa light chain.
Volume du lit
25 mL
Débit
300 cm/hr.
Type de ligand
Alkaline Stabilized Protein L-derived (E. coli)
Plage de pH
2 to 10
Granulométrie
60 μm
Marque
Cytiva
MabSelect™ VL resin with a redesigned protein L ligand for high binding capacity and improved alkaline stability. For affinity capture of antibody Fabs, bispecifics, and other variants containing a kappa light chain.
As the diversity of antibody variants increases, so does the need for chromatography resins that can capture and purify these variants. As an alternative to protein A, protein L resin can be used to capture antibody Fabs, bispecific antibodies, and other molecules containing kappa variants of the variable light (VL) chain. Protein L binds human kappa light chain subtypes 1, 3, and 4 and mouse kappa light chain subtype 1.
Caractéristiques principales
High dynamic binding capacity protein L resin for efficient capture of antibody Fabs, bispecifics, and variants containing a kappa light chain
Stable when cleaned with 0.1 M NaOH, reducing risk for bioburden incidents
Provides good resolution for product-related impurities in the capture of bispecific antibodies
Caractéristiques techniques
Marque
Cytiva
Réf. B-LABO
BL-RE-128241
Réf. fabricant
17827774
Volume du lit
25 mL
Débit
300 cm/hr.
Type de ligand
Alkaline Stabilized Protein L-derived (E. coli)
Plage de pH
2 to 10
Granulométrie
60 μm
Contenu et stockage
2°C to 8°C, 20% Ethanol
À utiliser avec (application)
Antibody Affinity Chromatography
dimMatrix
VL Protein L Resin
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