"/> Novus Biologicals™ Pam3CSK4, TLR1 and TLR2 Ligand | B-LABO France

Novus Biologicals™ Pam3CSK4, TLR1 and TLR2 Ligand

Réf. : BL-RE-128336Réf. fabricant : 18705143 0.025 mg
224,62 € HT

Applications: Functional, In vitro assay, In vivo assay, Ligand Activation

Concentration
0.5 mg/mL
Contenu et stockage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Quantité
0.025 mg
À utiliser avec (application)
Activation of TLR1 and TLR2 heterodimer. Stimulation of TLR1 and TLR2 has been reported with 10 to 100ng/mL. Use in vitro assay reported in scientific literature (PMID: 24105263) Use in functional reported in scientific literature (PMID 25511699). Use in In-vivo reported in scientific literature (PMID 25466255). Use in ligand activation reported in multiple pieces scientific literature.
Cible
Pam3CSK4, TLR1 and TLR2 Ligand
Marque
Novus Biologicals

Pam3CSK4, TLR1 and TLR2 Ligand is a synthetic tripalmitoylated lipohexapeptide analog of the immunologically active N-terminal portion of bacterial lipoprotein. It activates monocytes and macrophages and is also a potent activator of proinflammatory transcription factor NF-kB. Pam3CSK4, TLR1 and TLR2 Ligand is recognized by a heterodimer formed between TLR1 and TLR2. Pam3CSK4, TLR1 and TLR2 Ligand stimulation: If your cell line does not naturally express TLR1+ TLR2, co-transfect with plasmids pCMV/TLR1and pCMV/TLR2. Forty-eight hours after transfection, stimulate cells with 10 to 100ng/ml of Pam3CSK4 for 6 to 24 hours. Determine Pam3CSK4 stimulation using appropriate detection assays. Buffer: Sterile water

Caractéristiques techniques

MarqueNovus Biologicals
Réf. B-LABOBL-RE-128336
Réf. fabricant18705143
Concentration0.5 mg/mL
Contenu et stockageStore at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Quantité0.025 mg
À utiliser avec (application)Activation of TLR1 and TLR2 heterodimer. Stimulation of TLR1 and TLR2 has been reported with 10 to 100ng/mL. Use in vitro assay reported in scientific literature (PMID: 24105263) Use in functional reported in scientific literature (PMID 25511699). Use in In-vivo reported in scientific literature (PMID 25466255). Use in ligand activation reported in multiple pieces scientific literature.
CiblePam3CSK4, TLR1 and TLR2 Ligand
EspècesHuman/Mouse
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