Thermo Scientific™ EZ-Link™ TFP Ester-PEG4-DBCO

Réf. : p-9597000
206.00€ - 279.00€€

An amine reactive heterobifunctional crosslinker which contains a dibenzylcyclooctyne (DBCO) group for copper-free click chemistry applications. The crosslinker can be used to label a variety of amine containing molecules such as proteins, biomolecules, or small molecules.

Réactivité chimique
Amine-Azide
Cleavable
No
Description
TFP Ester-PEG4-DBCO
Poids moléculaire
714.7
Pégylé
Yes
Marque
Thermo Scientific™

Référence Prix Marque Quantité Ajouter
17621586 206.00€ - 279.00€ Thermo Scientific™ 10 x 1 mg
17514346 206.00€ - 279.00€ Thermo Scientific™ 10 x 1 mg
  • An amine reactive heterobifunctional crosslinker which contains a dibenzylcyclooctyne (DBCO) group for copper-free click chemistry applications
  • The crosslinker can be used to label a variety of amine containing molecules such as proteins, biomolecules, or small molecules
  • Once a protein or (bio)molecule is DBCO labeled, it can undergo a copper-free azide-alkyne cycloaddition reaction to form a stable triazole linkage with an azide labeled coupling partner
  • Can be used to create diverse conjugates with the biorthogonal coupling between an alkyne and azide (supplied separately)
  • The coupling or crosslinking procedure is typically done in two steps
    • First, a protein or amine containing molecule is labeled with a DBCO group and excess crosslinker is removed
    • Second, an azide containing moiety (prepared independently) is introduced into the same system as the DBCO moiety
    • Labeling occurs under biological conditions without the introduction of any additional reagents such as a copper catalyst
  • Ragent readily dissolves in water-miscible solvents for dilution into aqueous reaction mixtures
  • TFP esters are more hydrolytically stable than NHS esters
Réactivité chimique
Amine-Azide
Cleavable
No
Description
TFP Ester-PEG4-DBCO
Poids moléculaire
714.7
Pégylé
Yes
Longueur du bras espaceur
17.9 Å
Contenu et stockage
Upon receipt store desiccated at -20°C.
Perméabilité cellulaire
Not determined
Conditions d’expédition
Wet Ice
Gamme de produits
EZ-Link™ No-Weigh™
Méthode d’étiquetage
Chemical Labeling
Type d’agent de réticulation
Heterobifunctional
Groupement de réactifs
TFP Ester, DBCO
Entretoise
Medium (10 to 30 Å)
Quantité
10 x 1 mg
Solubilité
DMF, DMSO
Format
Standard, Single-use
Hydrosoluble
No
Type de produit
Crosslinker