"/>
Thermo Scientific™ EZ-Link™ TFP Ester-PEG4-D… | B-LABO France
Thermo Scientific™ EZ-Link™ TFP Ester-PEG4-DBCO
Réf. : BL-RE-129635Réf. fabricant : 17514346 10 x 1 mg
206,00 € HT
An amine reactive heterobifunctional crosslinker which contains a dibenzylcyclooctyne (DBCO) group for copper-free click chemistry applications. The crosslinker can be used to label a variety of amine containing molecules such as proteins, biomolecules, or small molecules.
Réactivité chimique
Amine-Azide
Cleavable
No
Description
TFP Ester-PEG4-DBCO
Poids moléculaire
714.7
Pégylé
Yes
Marque
Thermo Scientific
Caractéristiques principales
An amine reactive heterobifunctional crosslinker which contains a dibenzylcyclooctyne (DBCO) group for copper-free click chemistry applications
The crosslinker can be used to label a variety of amine containing molecules such as proteins, biomolecules, or small molecules
Once a protein or (bio)molecule is DBCO labeled, it can undergo a copper-free azide-alkyne cycloaddition reaction to form a stable triazole linkage with an azide labeled coupling partner
Can be used to create diverse conjugates with the biorthogonal coupling between an alkyne and azide (supplied separately)
The coupling or crosslinking procedure is typically done in two stepsFirst, a protein or amine containing molecule is labeled with a DBCO group and excess crosslinker is removedSecond, an azide containing moiety (prepared independently) is introduced into the same system as the DBCO moietyLabeling occurs under biological conditions without the introduction of any additional reagents such as a copper catalyst
First, a protein or amine containing molecule is labeled with a DBCO group and excess crosslinker is removed
Second, an azide containing moiety (prepared independently) is introduced into the same system as the DBCO moiety
Labeling occurs under biological conditions without the introduction of any additional reagents such as a copper catalyst
Ragent readily dissolves in water-miscible solvents for dilution into aqueous reaction mixtures
TFP esters are more hydrolytically stable than NHS esters
Caractéristiques techniques
Marque
Thermo Scientific
Réf. B-LABO
BL-RE-129635
Réf. fabricant
17514346
Réactivité chimique
Amine-Azide
Cleavable
No
Poids moléculaire
714.7
Pégylé
Yes
Longueur du bras espaceur
17.9 Å
Contenu et stockage
Upon receipt store desiccated at -20°C.
Perméabilité cellulaire
Not determined
Conditions d’expédition
Wet Ice
Gamme de produits
EZ-Link™ No-Weigh™
Méthode d’étiquetage
Chemical Labeling
Type d’agent de réticulation
Heterobifunctional
Groupement de réactifs
TFP Ester, DBCO
Entretoise
Medium (10 to 30 Å)
Forme
Solid
Quantité
10 x 1 mg
Solubilité
DMF, DMSO
Format
Standard, Single-use
Hydrosoluble
No
Type de produit
Crosslinker
Une question, une configuration particulière ? Contactez-nous pour un devis.
