Desmosomes are cell-cell junctions between epithelial, myocardial, and certain other cell types. Currently, three desmoglein subfamily members have been identified and all are members of the cadherin cell adhesion molecule superfamily. These desmoglein gene family members are located in a cluster on chromosome 18. This protein has been identified as the autoantigen of the autoimmune skin blistering disease pemphigus vulgaris.
Caractéristiques techniques
| Marque | Invitrogen |
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| Réf. B-LABO | BL-RE-143747 |
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| Réf. fabricant | 18557844 |
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| Numéro d’adhésion | Cadherin family member 4; CDHF4; desmoglein 1; desmoglein 1 beta; desmoglein 1 gamma; desmoglein-1; Desmosomal glycoprotein 1; DG1; DSG; DSG1; Dsg1b; Dsg1c; EPKHE; EPKHIA; Pemphigus foliaceus antigen; PPKS1; SPPK1 |
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| Plage de dosage | 0.82 to 200 ng/mL |
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| Sensibilité du dosage | 0.82 ng/mL |
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| Conjugué | Biotin |
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| Type de produit | ELISA |
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| Type d’échantillon | Serum |
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| À utiliser avec (équipement) | Colorimetric Microplate Reader |
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| Identification génétique (Entrez) | Q02413 |
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| Symbole de gène(s) | DSG1 |
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| Coefficient de variation inter-dosage | <12% |
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| Coefficient de variation intra-dosage | <10% |
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| Contenus des kits | Pre-coated 96 well plate, Standard, Assay Diluent concentrate, Biotinylated Detection Antibody, SAV-HRP, Wash Buffer, Chromogen, Stop Solution, Adhesive Plate Covers |
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| Marqueur ou colorant | HRP |
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| Quantité | 10 x 96 Tests |
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| État réglementaire | Research Use Only |
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| Volume d’échantillon | Plasma, 50 µL; Serum, 50 µL; Supernatant, 50 µL |
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| Conditions de stockage | 2°C to 8°C |
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| Cible | Desmoglein 1 |
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| Heure du test | 1 hr 20 min |
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| Durée totale du dosage | 4 hr 45 min |
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