ADAMTS-1 is a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motif) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The protein encoded by this gene contains two disintegrin loops and three C-terminal TS motifs and has anti-angiogenic activity. The expression of this gene may be associated with various inflammatory processes as well as development of cancer cachexia. This gene is likely to be necessary for normal growth, fertility, and organ morphology and function.
Caractéristiques techniques
| Marque | Invitrogen |
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| Réf. B-LABO | BL-RE-143881 |
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| Réf. fabricant | 18577864 |
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| Numéro d’adhésion | a disintegrin and metalloproteinase; A disintegrin and metalloproteinase with thrombospondin motifs 1; a disintegrin and metalloproteinase with thrombospondin motifs 1 (ADAMTS-1); a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 1; a disintegrin-like and metallopeptidse (reprolysin type) with thrombospondin type 1 motif, 1; a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 1; ADAM; ADAM metallopeptidase with thrombospondin type 1 motif 1; ADAM metallopeptidase with thrombospondin type 1 motif, 1; ADAMs; ADAMTS; ADAM-TS 1; Adamts1; ADAM-TS1; ADAMTS-1; C3-C5; human metalloproteinase with thrombospondin type 1 motifs; KIAA1346; metalloendopeptidases; METH1; METH-1 |
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| Plage de dosage | 0.4 to 100 ng/mL |
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| Sensibilité du dosage | 0.4 ng/mL |
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| Conjugué | Biotin |
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| Type de produit | ELISA |
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| Type d’échantillon | Plasma |
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| À utiliser avec (équipement) | Colorimetric Microplate Reader |
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| Identification génétique (Entrez) | P97857 |
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| Symbole de gène(s) | ADAMTS1 |
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| Coefficient de variation inter-dosage | <12% |
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| Coefficient de variation intra-dosage | <10% |
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| Contenus des kits | Pre-coated 96 well plate, Standard, Assay Diluent concentrate, Biotinylated Detection Antibody, SAV-HRP, Wash Buffer, Chromogen, Stop Solution, Adhesive Plate Covers |
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| Marqueur ou colorant | HRP |
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| Quantité | 10 x 96 Tests |
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| État réglementaire | Research Use Only |
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| Volume d’échantillon | Serum, 50 µL; Supernatant, 50 µL; Plasma, 50 µL |
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| Conditions de stockage | 2°C to 8°C |
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| Cible | ADAMTS1 |
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| Heure du test | 1 hr 20 min |
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| Durée totale du dosage | 4 hr 45 min |
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