Denatured ANGPTL4 293T cell overexpression lysate
This gene is a member of the angiopoietin/angiopoietin-like gene family and encodes a glycosylated, secreted protein with a fibrinogen C-terminal domain. This gene is induced under hypoxic conditions in endothelial cells and is the target of peroxisome proliferation activators. The encoded protein is a serum hormone directly involved in regulating glucose homeostasis, lipid metabolism, and insulin sensitivity and also acts as an apoptosis survival factor for vascular endothelial cells. The encoded protein may play a role in several cancers and it also has been shown to prevent the metastatic process by inhibiting vascular activity as well as tumor cell motility and invasiveness. Decreased expression of this protein has been associated with type 2 diabetes. Alternatively spliced transcript variants encoding different isoforms have been described. This gene was previously referred to as ANGPTL2 but has been renamed ANGPTL4. (provided by RefSeq)
Western Blotting
| Marque | Abnova |
|---|---|
| Réf. B-LABO | BL-RE-144974 |
| Réf. fabricant | 16166616 |
| À utiliser avec (application) | Western Blot |
| Lignée cellulaire | 293T |
| Numéro d’ordre du gène | NM_139314 |
| Poids moléculaire | 45.2 |
| Plage de pH | 6.8 |
| Plasmide | pCMV-ANGPTL4 full-length |
| Test du contrôle qualité | Transient overexpression cell Lysate was tested with Anti-ANGPTL4 antibody (H00051129-B01) by western blotting |
| Quantité | 100 μL |
| Tampon de stockage | 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue) |
| Espèces hôtes | Human |
| Contenu et stockage | Store at -80°C. Aliquot to avoid repeated freezing and thawing. |
