Shp2 (PTPN11) inhibitor
PHPS1 sodium salt is a Shp2 (PTPN11) inhibitor (IC50 = 2.1 μM). Inhibits hepatocyte growth factor-stimulated epithelial cell scattering and branching morphogenesis
in vitro
. Increases myelin basic protein (MBP) levels in zebrafish embryo spinal cord. Also ameliorates bleomycin-induced pulmonary and dermal fibrosis
in vivo
| Marque | Tocris |
|---|---|
| Réf. B-LABO | BL-RE-151105 |
| Réf. fabricant | 18084892 |
| Quantité | 5 mg |
| Formule moléculaire | C<sub>21</sub>H<sub>14</sub>N<sub>5</sub>O<sub>6</sub>SNa |
| Poids de la formule | 487.42 |
| Type de produit | Inhibitor |
| Pureté | 98% |
