Selective and potent TAG Degrader for auxin-inducible degron 2 system; 5-Ph-IAA analog
5-Ph-IAA-AM is a potent and selective "Bump & Hole" TAG Degrader, for use within an auxin-inducible degron (AID2) system; it is an egg-permeant analog of 5-Ph-IAA (Cat. No. 7392). 5-Ph-IAA-AM induces selective degradation of a target protein tagged with a single-point mutant AtTIR1F79G F-box protein. 5-Ph-IAA-AM induces target protein degradation in
C. elegans
embryos. No developmental abnormality is observed when the embryos are treated with 50 μM 5-Ph-IAA-AM.
| Marque | Tocris Bioscience |
|---|---|
| Réf. B-LABO | BL-RE-151179 |
| Réf. fabricant | 18726305 |
| Nom chimique ou matériau | Acetoxymethyl 2-(5-phenyl-1H-indol-3-yl)acetate |
| Quantité | 50 mg |
| Cible | TAG Degradation Platforms |
| Formule moléculaire | C<sub>19</sub>H<sub>17</sub>NO<sub>4</sub> |
| Pureté | 0.98 |
