Functionalized IAP ligand for PROTACs
A 410099.1, amine is a functionalized IAP ligand for PROTAC® research and development. Boc protected A 410099.1 (Cat.No. 6470). Supplied with an amine functional handle for ready conjugation to a linker/target protein ligand. NanoBRET assays show EC50 values of 4.6, 9.2 and 15.6 nM for cIAP1, cIAP2 and XIAP proteins, respectively. Part of a range of functionalized tool molecules for PROTAC R&D. Please contact us for SD files of our available Degrader Building Blocks.
PROTAC® is a registered trademark of Arvinas Operations, Inc., and is used under license.
| Marque | Tocris Bioscience |
|---|---|
| Réf. B-LABO | BL-RE-151277 |
| Réf. fabricant | 18736806 |
| Nom chimique ou matériau | tert-Butyl [(S)-1-[[(S)-2-[(2S,4S)-4-amino-2-[[(R)-1,2,3,4-tetrahydronaphthalen-1-yl]carbamoyl]pyrrolidin-1-yl]-1-cyclohexyl-2-oxoethyl]amino]-1-oxopropan-2-yl](methyl)carbamate hydrochloride |
| CAS | 2374122-37-7 |
| Quantité | 100 mg |
| Formule moléculaire | C<sub>32</sub>H<sub>49</sub>N<sub>5</sub>O<sub>5</sub>.HCl |
| Pureté | 98% |
