"/> Tocris Bioscience™ NG 25 | B-LABO France

Tocris Bioscience™ NG 25

Name: Tocris Bioscience™ NG 25
Brand: Tocris Bioscience
SKU: 18723439
Price: 412.52 EUR
Availability: InStock

Réf. : BL-RE-151345Réf. fabricant : 18723439 5 mg

412,52 € HT

TGF-β-activated kinase (TAK1) inhibitor

Nom chimique ou matériau: N-[4-[(4-Ethyl-1-piperazinyl)methyl]-3-(trifluoromethyl)phenyl]-4-methyl-3-(1H-pyrrolo[2,3-b]pyridin-4-yloxy)benzamide
CAS: 1315355-93-1
Quantité: 5 mg
Cible: Other Kinase Inhibitors
Formule moléculaire: C₂₉H₃₀F₃N₅O₂
Marque: Tocris Bioscience

NG 25 is a TGF-β-activated kinase (TAK1) inhibitor (IC50 = 149 nM). Also inhibits LYN, MAP4K2 and Abl kinase activity (IC50 values are 12.9, 21.7 and 75.2 nM, respectively). Suppresses CpG A and CpG B-stimulated secretion of IFN-α and TLR7/8 agonist CL097-stimulated secretion of IFN-β in Gen 2.2 leukemia cells

in vitro

Caractéristiques techniques

Marque	Tocris Bioscience
Réf. B-LABO	BL-RE-151345
Réf. fabricant	18723439
Nom chimique ou matériau	N-[4-[(4-Ethyl-1-piperazinyl)methyl]-3-(trifluoromethyl)phenyl]-4-methyl-3-(1H-pyrrolo[2,3-b]pyridin-4-yloxy)benzamide
CAS	1315355-93-1
Quantité	5 mg
Cible	Other Kinase Inhibitors
Formule moléculaire	C<sub>29</sub>H<sub>30</sub>F<sub>3</sub>N<sub>5</sub>O<sub>2</sub>
Poids de la formule	537.58
Pureté	>98%

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Tocris Bioscience™ NG 25

Caractéristiques techniques

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