ML 418 is a Kir7.1 inhibitor (IC50 = 0.31 μM). Also inhibits Kir6.2 with similar potency. Displays >17-fold selectivity for Kir7.1 over Kir1.1, Kir2.1, Kir2.2, Kir2.3, Kir3.1/3.2 and Kir4.1. Active in vivo.
- Nom chimique ou matériau
- Isopropyl (1-((5-chloro-8-hydroxyquinolin-7-yl)methyl)piperidin-4-yl)carbamate
- CAS
- 1928763-08-9
- Quantité
- 50 mg
- Formule moléculaire
- C19H24CIN3O3
- Pureté
- 98%
