"/> Tocris Bioscience™ VTP 27999 trifluoroacetate | B-LABO France

Tocris Bioscience™ VTP 27999 trifluoroacetate

Réf. : BL-RE-151644Réf. fabricant : 18763979 10 mg
172,78 € HT

Highly potent and selective renin inhibitor

Nom chimique ou matériau
Methyl N-[2-[(R)-(3-Chlorophenyl)[(3R)-1-[[[(2S)-2-(methylamino)-3-[(3R)-tetrahydro-2H-pyran-3-yl]propyl]amino]carbonyl]-3-piperidinyl]methoxy]ethyl]carbamate trifluoroacetate
CAS
1013937-63-7
Quantité
10 mg
Cible
Additional Synthetic Protease Inhibitors
Formule moléculaire
C26H41ClN4O5.CF3CO2H
Marque
Tocris Bioscience

VTP 27999 trifluoroacetate is a highly potent and selective renin inhibitor (IC50 = 0.47 nM). Displays >1000-fold selectivity over related and unrelated off-targets. Blocks renin-stimulated ERK1/2 phosphorylation in vascular smooth muscle cells. Exhibits a different mode of action to aliskiren (Cat. No. 5491).

Caractéristiques techniques

MarqueTocris Bioscience
Réf. B-LABOBL-RE-151644
Réf. fabricant18763979
Nom chimique ou matériauMethyl N-[2-[(R)-(3-Chlorophenyl)[(3R)-1-[[[(2S)-2-(methylamino)-3-[(3R)-tetrahydro-2H-pyran-3-yl]propyl]amino]carbonyl]-3-piperidinyl]methoxy]ethyl]carbamate trifluoroacetate
CAS1013937-63-7
Quantité10 mg
CibleAdditional Synthetic Protease Inhibitors
Formule moléculaireC<sub>26</sub>H<sub>41</sub>ClN<sub>4</sub>O<sub>5</sub>.CF<sub>3</sub>CO<sub>2</sub>H
Poids de la formule639.1
Pureté>97%
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