(+)-Bay K8644, a modulator of potential operated calcium channels, exists as two enantiomers that have opposite actions (Hess et al.; Nowycky et al.; O'Neill et al.; Ravens et al.; Yamamoto et al.) (+)-Bay K8644 is an L-type channel blocker that has negative inotropic and vasodilatory effects (Artigas et al.; Franckowiak et al.; Ravens et al.)
When combined with BIX-01294, enables reprogramming of mouse embryonic fibroblasts after transduction with OCT4 and KLF4 only (Shi et al.)
Increases neuronal differentiation from neural stem and progenitor cells (NSCs) derived from the brains of postnatal mice (D'Ascenzo et al.)
Caractéristiques techniques
Marque
STEMCELL Technologies
Réf. B-LABO
BL-RE-151704
Réf. fabricant
17110062
CAS
98791-67-4
Synonyme
(+)-Bay-K 8644; (+)-Bay-R 4407; (R)-(+)-Bay K 8644; NI 105; R 4407