MS 15203 is a potent and selective GPR171 partial agonist (EC50 = 90 nM; 28% inhibition of Forskolin activated adenylyl cyclase activity in rat hypothalamic membranes). Exhibits minimal binding to a panel of ∼70 GPCRs and 10 other receptors (<22% of radioligand displaced from the target receptors). Increases neuronal activity in the paraventricular nucleus. Increases food intake and body weight in mice.
- Nom chimique ou matériau
- 5-[(2-Methyl-1-oxo-2-propen-1-yl)amino]-1,3-benzenedicarboxylic acid
- CAS
- 73912-52-4
- Plage de pourcentage du dosage
- >98%
- Quantité
- 25 mg
- Formule moléculaire
- C12H11NO5
- Poids de la formule
- Observed MW: 249.22
