DG 041 is a potent and selective EP3 antagonist (IC50 = 4.6 nM). Inhibits PGE2 facilitation of platelet aggregation in vitro and ex vivo. Displays good plasma and metabolic stability. Does not affect bleeding time in rats. Antiplatelet and antithrombotic.
- Nom chimique ou matériau
- (2E)-3-[1-[(2,4-Dichlorophenyl)methyl]-5-fluoro-3-methyl-1H-indol-7-yl]-N-[(4,5-dichloro-2-thienyl)sulfonyl]-2-propenamide
- CAS
- 861238-35-9
- Quantité
- 50 mg
- Cible
- Prostanoid Receptor Antagonists
- Formule moléculaire
- C23H15Cl4FN2O3S2
- Pureté
- 0.98
