"/> Tocris Bioscience™ H 151 | B-LABO France

Tocris Bioscience™ H 151

Réf. : BL-RE-158109Réf. fabricant : 18717606 10 mg
239,73 € HT

STING antagonist

Nom chimique ou matériau
N-(4-Ethylphenyl)-N'-1H-indol-3-yl-urea
CAS
941987-60-6
Synonyme
ERIS, hMITA, MITA, mitochondrial mediator of IRF3 activation, MPYS, NET23, N-terminal methionine-proline-tyrosine-serine plasma membrane tetraspanner, sting, transmembrane protein 173
Quantité
10 mg
Cible
STING Antagonists
Marque
Tocris Bioscience

H 151 is a STING antagonist. Covalently binds STING at Cys91, blocking palmitoylation and preventing assembly of STING clusters. Decreases inflammatory cytokine production in human and mouse cells

in vitro

. Also blocks CMA (Cat. No. 6677) -induced increases in levels of inflammatory cytokines in mice, and alleviates systemic inflammation in a mouse model of autoinflammatory disease.

Caractéristiques techniques

MarqueTocris Bioscience
Réf. B-LABOBL-RE-158109
Réf. fabricant18717606
Nom chimique ou matériauN-(4-Ethylphenyl)-N'-1H-indol-3-yl-urea
CAS941987-60-6
SynonymeERIS, hMITA, MITA, mitochondrial mediator of IRF3 activation, MPYS, NET23, N-terminal methionine-proline-tyrosine-serine plasma membrane tetraspanner, sting, transmembrane protein 173
Quantité10 mg
CibleSTING Antagonists
Formule moléculaireC<sub>17</sub>H<sub>17</sub>N<sub>3</sub>O
Poids de la formule279.34
Pureté98%
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