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Thermo Scientific™ CaptureSelect™ LambdaXP Affinity Matrix

Réf. : BL-RE-158294Réf. fabricant : 18476508 10 mL
1 596,00 € HT

CaptureSelect LambdaXP Affinity Matrix was specifically designed for the purification of recombinant human immunoglobulins and Fab fragments containing a lambda light chain.

Capacité de liaison
>30 g IgG/L resin
Débit
50 to 200 cm/hr. (Up to 2 bar)
Formule
50% slurry suspension in 20% ethanol
Matrice
Agarose-based, epoxide-activated
Contenu et stockage
Store in refrigerator (2°C to 8°C), protect from daylight.
Marque
Thermo Scientific

Features of this affinity matrix include:

CaptureSelect LambdaXP Affinity Matrix can be utilized for the purification of human Ig's and Fab/Fab2 fragments directly from complex source materials and enables a robust and efficient purification process with excellent purity obtained in a single step.

Points forts

Free of animal components

CaptureSelect products contain affinity ligands based on recombinant single-domain antibody fragments (VHH) created by a proprietary technology. The VHH affinity ligand is a 12 to 15 kDa fragment comprising the three complementarity-determining regions (CDRs) that form the antigen-binding domain, efficiently produced in the yeast Saccharomyces cerevisiae by a production process free of any animal components (Animal Origin-Free).

Main characteristics

  • Matrix: agarose-based, epoxide-activated
  • Average particle size: 65 ± 10 μm
  • Ligand: CaptureSelect LambdaXP
  • Ligand coupling method: epoxide coupling
  • Binding capacity: >30 g IgG/L resin depending on flow rate, column height, and contact time
  • Elution conditions: 25 mM sodium acetate, pH 3.5

Caractéristiques principales

  • Efficient elution of Fab fragments and immunoglobulins containing a lambda light chain, no cross binding to the Fc-region or kappa light chains
  • One-step purification from crude material with high purity and yield
  • Excellent scalability
  • Non-animal-derived

Caractéristiques techniques

MarqueThermo Scientific
Réf. B-LABOBL-RE-158294
Réf. fabricant18476508
Capacité de liaison>30 g IgG/L resin
Débit50 to 200 cm/hr. (Up to 2 bar)
Formule50% slurry suspension in 20% ethanol
MatriceAgarose-based, epoxide-activated
Contenu et stockageStore in refrigerator (2°C to 8°C), protect from daylight.
Pression de fonctionnement max.2 bar
Conditions d’expéditionShips at 2°C to 8°C
Granulométrie65 ± 10 μm
FormeAgarose Bead
Gamme de produitsCaptureSelect™
Quantité10 mL
À utiliser avec (application)Lambda Fab purification
CibleLambda light chain
TypeAffinity Matrix
Type de ligandLambdaXP
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