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Thermo Scientific™ CaptureSelect™ LambdaXP Affinity Matrix

Réf. : BL-RE-158295Réf. fabricant : 18486658 50 mL
Prix sur devis
Tarif personnalisé selon la configuration et la quantité.

CaptureSelect LambdaXP Affinity Matrix was specifically designed for the purification of recombinant human immunoglobulins and Fab fragments containing a lambda light chain.

Capacité de liaison
>30 g IgG/L resin
Débit
50 to 200 cm/hr. (Up to 2 bar)
Formule
50% slurry suspension in 20% ethanol
Matrice
Agarose-based, epoxide-activated
Contenu et stockage
Store in refrigerator (2°C to 8°C), protect from daylight.
Marque
Thermo Scientific

Features of this affinity matrix include:

CaptureSelect LambdaXP Affinity Matrix can be utilized for the purification of human Ig's and Fab/Fab2 fragments directly from complex source materials and enables a robust and efficient purification process with excellent purity obtained in a single step.

Points forts

Free of animal components

CaptureSelect products contain affinity ligands based on recombinant single-domain antibody fragments (VHH) created by a proprietary technology. The VHH affinity ligand is a 12 to 15 kDa fragment comprising the three complementarity-determining regions (CDRs) that form the antigen-binding domain, efficiently produced in the yeast Saccharomyces cerevisiae by a production process free of any animal components (Animal Origin-Free).

Main characteristics

  • Matrix: agarose-based, epoxide-activated
  • Average particle size: 65 ± 10 μm
  • Ligand: CaptureSelect LambdaXP
  • Ligand coupling method: epoxide coupling
  • Binding capacity: >30 g IgG/L resin depending on flow rate, column height, and contact time
  • Elution conditions: 25 mM sodium acetate, pH 3.5

Caractéristiques principales

  • Efficient elution of Fab fragments and immunoglobulins containing a lambda light chain, no cross binding to the Fc-region or kappa light chains
  • One-step purification from crude material with high purity and yield
  • Excellent scalability
  • Non-animal-derived

Caractéristiques techniques

MarqueThermo Scientific
Réf. B-LABOBL-RE-158295
Réf. fabricant18486658
Capacité de liaison>30 g IgG/L resin
Débit50 to 200 cm/hr. (Up to 2 bar)
Formule50% slurry suspension in 20% ethanol
MatriceAgarose-based, epoxide-activated
Contenu et stockageStore in refrigerator (2°C to 8°C), protect from daylight.
Pression de fonctionnement max.2 bar
Conditions d’expéditionShips at 2°C to 8°C
Granulométrie65 ± 10 μm
FormeAgarose Bead
Gamme de produitsCaptureSelect™
Quantité50 mL
À utiliser avec (application)Lambda Fab purification
CibleLambda light chain
TypeAffinity Matrix
Type de ligandLambdaXP
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