Tocris Bioscience™ Colivelin

Ref : 18025832
398.40

STAT3 activator; also protects against β-amyloid neurotoxicity

Quantité :
500 μg
Brand
Tocris Bioscience™
Colivelin is a neuroprotective peptide and activator of STAT3. Protects neurons against the neurotoxic effects of amyloid β-peptide (1-43) at a concentration of 100 fM in vitro. Suppresses neuronal death by activating STAT3 in vitro; upregulates cholinergic transmission and ameliorates memory impairment in Alzheimer's disease (AD) models. Also prevents alcohol-induced apoptosis in a fetal mouse model. Brain penetrant.

Quantité : 500 μg

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