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Ref : 17110212

958.50

Antibiotic; Protein synthesis inhibitor

CAS :

58-58-2

Pourcentage de pureté :

≥98%

Quantité :

500 mg

Brand

STEMCELL Technologies

Puromycin is an aminonucleoside antibiotic, derived from Streptomyces alboniger, which acts as a protein synthesis inhibitor
It binds to the target ribosome site A, where it is transferred to the growing polypeptide chain causing premature chain termination (Lührmann et al.; Rodriguez-Fonseca et al.; Azzam & Algranati)
A biologically inactive form is generated when puromycin is N-acetylated by puromycin-N-acetyltransferase, allowing this gene to be used as a selective resistance marker (Vara et al.) 1985)
Selects for cells expressing puromycin-N-acetyltransferase resistance gene as a research tool (de la Luna & Ortín; Iwaki et al.)
Useful in CRISPR/Cas9 mammalian gene editing by selecting for successful Cas9-induced knock-in with puromycin resistance gene (Park et al.)
Possesses anti-tumor activity when tested against numerous cell lines (Foley & Eagle)

CAS : 58-58-2

Pourcentage de pureté : ≥98%

Quantité : 500 mg

Corning™ Nutriment F-12K cellgro™ 217.54

Gibco™ Enzyme (1X) TrypLE™ Express, sans rouge de phénol 31.33€ - 718.00€