"/> Tocris Bioscience™ BDY FL Thalidomide | B-LABO France

Tocris Bioscience™ BDY FL Thalidomide

Réf. : BL-RE-160755Réf. fabricant : 18775855 2 mg
307,77 € HT

High affinity fluorescent probe for TR-FRET cereblon binding assay

Nom chimique ou matériau
3-(5,5-Difluoro-7,9-dimethyl-5 H-5λ4,6λ4-dipyrrolo[1,2-c:2 ',1 '-f][1,3,2 ]diazaborinin-3-yl)-N-(8-(2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)acetamido)octyl)propenamide
CAS
2740620-18-0
Quantité
2 mg
Cible
Fluorescent Probes
Formule moléculaire
C37H43BF2N6O7
Marque
Tocris Bioscience

BDY FL Thalidomide is a high-affinity fluorescent probe (Kd = 3.6 nM). It can be used in time-resolved fluorescence resonance energy-transfer (TR-FRET) cereblon binding assays for PROTAC™ Degrader development. This assay is highly sensitive, selective, and stable. Excitation and emission maxima (λ) are 502 and 510 nm, respectively.

PROTAC™ is a registered trademark of Arvinas Operations, Inc., and is used under license.

Caractéristiques techniques

MarqueTocris Bioscience
Réf. B-LABOBL-RE-160755
Réf. fabricant18775855
Nom chimique ou matériau3-(5,5-Difluoro-7,9-dimethyl-5 H-5λ4,6λ4-dipyrrolo[1,2-c:2 ',1 '-f][1,3,2 ]diazaborinin-3-yl)-N-(8-(2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)acetamido)octyl)propenamide
CAS2740620-18-0
Quantité2 mg
CibleFluorescent Probes
Formule moléculaireC<sub>37</sub>H<sub>43</sub>BF<sub>2</sub>N<sub>6</sub>O<sub>7</sub>
Pureté0.95
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