Alkyne containing monosaccharide building block; used in BOCTAG
Ac4GalN6yne is a cell-permeable alkyne-containing monosaccharide building block. It can be used in Bio-Orthogonal Cell-specific Tagging of Glycoproteins (BOCTAG) technique. In this strategy, cells carrying an artificial biosynthetic pathway (B. longum NahK and mut-AGX1) can generate alkyne-tagged UDP-GalN6yne, that are then used by glycosyltransferases to chemically tag the glycoproteome. Ac4GalN6yne can be used for bioorthogonal labelling
in vitro
and mouse models.
| Marque | Tocris Bioscience |
|---|---|
| Réf. B-LABO | BL-RE-160780 |
| Réf. fabricant | 30000444 |
| Nom chimique ou matériau | 2-Deoxy-2-[(1-oxo-5-hexyn-1-yl)amino]-D-galactopyranose-1,3,4,6-tetraacetate |
| Quantité | 10 mg |
| Cible | Glycobiology Probes |
| Formule moléculaire | C<sub>20</sub>H<sub>27</sub>NO<sub>10</sub> |
| Pureté | 95% |
