LDN 193189 in solution is a convenient and ready-to-use 10 mM sterile-filtered solution of LDN 193189 pre-dissolved in water. A potent and selective ALK2 and ALK3 inhibitor (IC50 values are 5 nM and 30 nM, respectively); inhibits BMP4-mediated Smad1/5/8 activation. Promotes neural induction of hPSCs in combination with SB 431542 (Cat. No. 1614). Also induces differentiation of hPSCs into nociceptive sensory neurons in combination with SB 431542 (Cat. No. 1614), SU 5402 (Cat. No. 3300), CHIR 99021 (Cat. No. 4423) and DAPT (Cat. No. 2634).
Caractéristiques techniques
| Marque | Tocris Bioscience |
|---|
| Réf. B-LABO | BL-RE-166591 |
|---|
| Réf. fabricant | 30130446 |
|---|
| Nom chimique ou matériau | 4-[6-[4-(1-Piperazinyl)phenyl]pyrazolo[1,5-a]pyrimidin-3-yl]quinoline dihydrochloride |
|---|
| CAS | 1435934-00-1 |
|---|
| Quantité | 6 mg |
|---|
| Cible | BMP and Other Activin Receptor Inhibitors |
|---|
| Formule moléculaire | C25H22N6.2HCl |
|---|
| Pureté | 0.97 |
|---|
Une question, une configuration particulière ?
Contactez-nous pour un devis.
