ELISA Kit
CCL5 (RANTES) is a chemokine gene located on the q-arm of chromosome 17. Chemokines are a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of the N-terminal cysteine residues of the mature peptide. CCL5, a member of the CC subfamily, functions as a chemoattractant for blood monocytes, memory T helper cells, and eosinophils. It causes the release of histamine from basophils and activates eosinophils. This cytokine is one of the major HIV-suppressive factors produced by CD8+ cells. It functions as one of the natural ligands for the chemokine receptor chemokine (C-C motif) receptor 5 (CCR5), and it suppresses in vitro replication of the R5 strains of HIV-1, which use CCR5 as a coreceptor. Alternative splicing results in multiple transcript variants that encode different isoforms. Diseases associated with CCL5 include Human Immunodeficiency Virus Type 1 and Periapical Granuloma.
| Marque | Invitrogen |
|---|---|
| Réf. B-LABO | BL-RE-166968 |
| Réf. fabricant | 30088241 |
| Numéro d’adhésion | P50231 |
| Plage de dosage | Lot-specific |
| Sensibilité du dosage | Lot-specific |
| Conjugué | HRP |
| Type de produit | ELISA Kit |
| À utiliser avec (équipement) | Colorimetric Microplate Reader |
| Identification génétique (Entrez) | 81780 |
| Symbole de gène(s) | CCL5 |
| Contenus des kits | This Rat CCL5 (RANTES) ELISA Kit includes Capture Antibody, Detection Antibody, Protein Standard, and HRP-conjugate. The HRP-conjugate is packaged separately. |
| Marqueur ou colorant | HRP |
| Quantité | 10 x 96 Tests |
| État réglementaire | RUO |
| Conditions de stockage | Refer to product documentation for component specific storage temperature. |
| Cible | Rat RANTES ELISA Development Kit (ABTS) |
| Heure du test | 1 hr 45 min |
| Durée totale du dosage | 24 hr 30 min |
