Members in the TNF superfamily regulate immune responses and induce apoptosis. Two novel members in the TNF family were recently identified and designated BAFF/BLyS/TALL-1/THANK/zTNF4 and April/TALL-2, respectively. BAFF was characterized as a B cell activator since it induced B cell proliferation and immunoglobulin secretion. April regulates immunological and non-immunological cell growth. Three receptors, BCMA, TACI, and BAFF-R, for BAFF and April were recently identified. TACI, like BCMA, binds BAFF and April. TACI and its ligands regulate humoral immune responses, activate NF-kappa-B and c-jun N-terminal kinase, and are involved in B cell associated autoimmune diseases.
Caractéristiques techniques
| Marque | Invitrogen |
| Réf. B-LABO | BL-RE-167007 |
| Réf. fabricant | 30089280 |
| Numéro d’adhésion | O14836 |
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| Plage de dosage | Lot-specific |
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| Sensibilité du dosage | Lot-specific |
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| Conjugué | HRP |
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| Type de produit | ELISA Kit |
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| À utiliser avec (équipement) | Colorimetric Microplate Reader |
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| Identification génétique (Entrez) | 23495 |
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| Symbole de gène(s) | TNFRSF13B |
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| Contenus des kits | This Human TACI ELISA Kit includes Capture Antibody, Detection Antibody, Protein Standard, and HRP-conjugate. The HRP-conjugate is packaged separately. |
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| Marqueur ou colorant | HRP |
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| Quantité | 10 x 96 Tests |
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| État réglementaire | RUO |
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| Conditions de stockage | Refer to product documentation for component specific storage temperature. |
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| Cible | Human TACI (TNFRSF13B) ELISA Development Kit (ABTS) |
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| Heure du test | 1 hr 45 min |
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| Durée totale du dosage | 24 hr 30 min |
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