ELISA Kit
NOV is a member of the CCN family of secreted, cysteine-rich regulatory proteins. The full-length NOV protein contains four structural domains that confer distinct, and sometimes opposing, biological activities. Elevated expression of NOV is associated with certain tumors, including Wilm's tumor and most nephroblastomas. However, in other tumor types and certain cancer cell lines, increased tumorigenicity and proliferation is correlated with decreased NOV expression. Additionally, NOV induces cell adhesion and cell migration by signaling through specific cell-surface integrins, and by binding to heparin sulfate proteoglycans and to fibulin 1C. NOV has also been reported to exert proangiogenic activities.
| Marque | Invitrogen |
|---|---|
| Réf. B-LABO | BL-RE-167111 |
| Réf. fabricant | 30087915 |
| Numéro d’adhésion | P48745 |
| Plage de dosage | Lot-specific |
| Sensibilité du dosage | Lot-specific |
| Conjugué | HRP |
| Type de produit | ELISA Kit |
| À utiliser avec (équipement) | Colorimetric Microplate Reader |
| Identification génétique (Entrez) | 4856 |
| Symbole de gène(s) | CCN3 |
| Contenus des kits | This Human NOV ELISA Kit includes Capture Antibody, Detection Antibody, Protein Standard, and HRP-conjugate. The HRP-conjugate is packaged separately. |
| Marqueur ou colorant | HRP |
| Quantité | 10 x 96 Tests |
| État réglementaire | RUO |
| Conditions de stockage | Refer to product documentation for component specific storage temperature. |
| Cible | Human NOV ELISA Development Kit (ABTS) |
| Heure du test | 1 hr 45 min |
| Durée totale du dosage | 24 hr 30 min |
