This gene encodes a member of the serpin superfamily of serine proteinase inhibitors. The protein is primarily secreted by axons in the brain, and preferentially reacts with and inhibits tissue-type plasminogen activator. It is thought to play a role in the regulation of axonal growth and the development of synaptic plasticity. Mutations in this gene result in familial encephalopathy with neuroserpin inclusion bodies (FENIB), which is a dominantly inherited form of familial encephalopathy and epilepsy characterized by the accumulation of mutant neuroserpin polymers. Multiple alternatively spliced variants, encoding the same protein, have been identified.
Caractéristiques techniques
| Marque | Invitrogen |
| Réf. B-LABO | BL-RE-167123 |
| Réf. fabricant | 30089524 |
| Numéro d’adhésion | Q99574 |
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| Plage de dosage | Lot-specific |
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| Sensibilité du dosage | Lot-specific |
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| Conjugué | HRP |
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| Type de produit | ELISA Kit |
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| À utiliser avec (équipement) | Colorimetric Microplate Reader |
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| Identification génétique (Entrez) | 5274 |
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| Symbole de gène(s) | Serpini1 |
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| Contenus des kits | This Human Neuroserpin ELISA Kit includes Capture Antibody, Detection Antibody, Protein Standard, and HRP-conjugate. The HRP-conjugate is packaged separately. |
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| Marqueur ou colorant | HRP |
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| Quantité | 10 x 96 Tests |
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| État réglementaire | RUO |
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| Conditions de stockage | Refer to product documentation for component specific storage temperature. |
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| Cible | Human Neuroserpin ELISA Development Kit (ABTS) |
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| Heure du test | 1 hr 45 min |
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| Durée totale du dosage | 24 hr 30 min |
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