TOKU-E™ Cefotaxime ReadyMade™ Solution | B-LABO France
TOKU-E™ Cefotaxime ReadyMade™ Solution
Réf. : BL-RE-168150Réf. fabricant : 30044051 10 x 1 mL · Colorless
97,14 € HT
Cefotaxime ReadyMade™ Solution is provided as a filter-sterilized solution of Cefotaxime Sodium in water.
Nom chimique ou matériau
Cefotaxime
Forme physique
Liquid
CAS
64485-93-4
Source
Semi-synthetic (Acremonium sp.)
Conditionnement
2 mL plastic vial
Marque
TOKU-E
Caractéristiques principales
CAS Number: 64485-93-4
Molecular Formula: C16H16N5NaO7S2
Molecular Weight: 447.45 g/mo
Storage Conditions: -20°C
Form: Liquid
Source: Semi-synthetic (Acremonium sp.)
Spectrum: Cefotaxime Sodium has broad-spectrum activity against a wide variety of Gram-positive and Gram-negative bacteria. However, unlike many cephalosporin antibiotics, Cefotaxime Sodium is not effective against Pseudomonas aeruginosa
Mechanism of Action: Like β-lactams, cephalosporins interfere with PBP (penicillin binding protein) activity involved in the final phase of peptidoglycan synthesis. PBPs are enzymes which catalyze a pentaglycine crosslink between alanine and lysine residues providing additional strength to the cell wall. Without a pentaglycine crosslink, the integrity of the cell wall is severely compromised and ultimately leads to cell lysis and death. Resistance to cephalosporins is commonly due to cells containing plasmid encoded β-lactamases. Cefotaxime Sodium however, is largely resistant to β-lactamases