Thermo Scientific™ POROS™ CaptureSelect™ IgM-XL Affinity Matrix is intended for the purification of human IgM, with no binding to other immunoglobulins.
Capacité de liaison
>5 g/L
Formule
20% Ethanol
Matrice
Cross-linked poly(styrene-divinylbenzene)
Granulométrie
50 μm
Forme
Resin Slurry
Marque
Thermo Scientific
POROS CaptureSelect IgM-XL Affinity Matrix is intended for the purification of human IgM, with no binding to other immunoglobulins.
Features of this affinity matrix include:
POROS CaptureSelect IgM-XL Affinity Matrix binds to the Fc part of IgM. The high selectivity and yields obtained using this affinity matrix enable a robust, fast, and efficient purification process with excellent purity obtained in one step.
Points forts
Free of animal components
CaptureSelect products contain affinity ligands based on recombinant single-domain antibody fragments (VHH) created by a proprietary technology. The VHH affinity ligand is a 12 to 15 kDa fragment comprising the three complementarity-determining regions (CDRs) that form the antigen-binding domain, efficiently produced in the yeast Saccharomyces cerevisiae by a production process free of any animal components (animal origin-free).
Main characteristics
Matrix: cross-linked poly(styrene-divinylbenzene)
Average particle size: 50 μm
Ligand: POROS CaptureSelect IgM-XL affinity ligand
Ligand coupling method: epoxide coupling
Binding capacity: >5 g/L resin (determined with polyclonal human IgM from serum)
Elution conditions: acidic elution with 0.1 M glycine, pH 3.0
Caractéristiques principales
IgM purification from plasma and serum
Purification of monoclonal IgM from cell cultures
Efficient purification of IgM with high yields and retained activity
Excellent scalability
Non-animal derived
High flow rates
Cross-reactivity towards mouse and rat IgM
Caractéristiques techniques
Marque
Thermo Scientific
Réf. B-LABO
BL-RE-168674
Réf. fabricant
30245355
Capacité de liaison
>5 g/L
Formule
20% Ethanol
Matrice
Cross-linked poly(styrene-divinylbenzene)
Granulométrie
50 μm
Forme
Resin Slurry
Gamme de produits
CaptureSelect™
Quantité
5 mL
À utiliser avec (application)
Purification of human IgM
Type
Affinity Matrix
Type de ligand
IgM-XL affinity ligand
Une question, une configuration particulière ? Contactez-nous pour un devis.