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Thermo Scientific™ CaptureSelect™ IgA-XL Affinity Matrix

Réf. : BL-RE-168697Réf. fabricant : 30245090 5 mL
996,00 € HT

Thermo Scientific™ CaptureSelect™ IgA-XL Affinity Matrix is intended for the purification of human IgA, with no binding to other immunoglobulins.

Débit
50–200 cm/hr. (up to 2 bar)
Formule
20% (v/v) ethanol
Contenu et stockage
Store at 2–8°C. Protect from direct sunlight.
Granulométrie
65 ±10 μm
Forme
Resin Slurry
Marque
Thermo Scientific

CaptureSelect IgA-XL Affinity Matrix is intended for the purification of human IgA, with no binding to other immunoglobulins. The IgA-XL affinity matrix provides improved binding capacities (>15 g/L IgA) and elution characteristics (full elution at pH 4) compared to CaptureSelect IgA Affinity Matrix.

Features of this affinity matrix include:

CaptureSelect IgA-XL Affinity Matrix binds to the Fc part of IgA. The high selectivity and yields obtained using IgA-XL Affinity Matrix enable a robust, fast, and efficient purification process with excellent purity obtained in one step.

Points forts

Animal origin statement

CaptureSelect products contain affinity ligands based on recombinant single-domain antibody fragments (VHH) created by a proprietary technology. The VHH affinity ligand is a 12–15 kDa fragment comprising the three complementarity-determining regions (CDRs) that form the antigen-binding domain, efficiently produced in the yeast Saccharomyces cerevisiae by a production process free of any animal components (animal origin-free).

Main characteristics

  • Matrix: agarose-based, epoxide activated
  • Average particle size: 65 ± 10 μm
  • Ligand: CaptureSelect IgA-XL affinity ligand
  • Ligand coupling method: epoxide
  • Binding capacity: > 15 g/L at 5 minutes residence time, tested with plasma-derived polyclonal IgA
  • Elution conditions: 20 mM sodium citrate, pH 4

Caractéristiques principales

  • Purification of all IgA serotypes: IgA1, IgA2, dimeric IgA, and S-IgA (secretory IgA)
  • IgA purification from plasma, serum, and recombinant sources
  • Efficient purification of IgA with high yields and retained activity
  • Excellent scalability
  • Non-animal-derived

Caractéristiques techniques

MarqueThermo Scientific
Réf. B-LABOBL-RE-168697
Réf. fabricant30245090
Débit50–200 cm/hr. (up to 2 bar)
Formule20% (v/v) ethanol
Contenu et stockageStore at 2–8°C. Protect from direct sunlight.
Granulométrie65 ±10 μm
FormeResin Slurry
Gamme de produitsCaptureSelect™
Quantité5 mL
À utiliser avec (application)Purification of all IgA subtypes (IgA1, IgA2, dimeric IgA, secretory IgA)
CibleIgA-Fc domain
TypeAffinity Matrix
Type de ligandCaptureSelect IgA-XL Affinity Ligand
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