Thermo Scientific™ CaptureSelect™ IgA-XL Affinity Matrix is intended for the purification of human IgA, with no binding to other immunoglobulins.
Débit
50–200 cm/hr. (up to 2 bar)
Formule
20% (v/v) ethanol
Contenu et stockage
Store at 2–8°C. Protect from direct sunlight.
Granulométrie
65 ±10 μm
Forme
Resin Slurry
Marque
Thermo Scientific
CaptureSelect IgA-XL Affinity Matrix is intended for the purification of human IgA, with no binding to other immunoglobulins. The IgA-XL affinity matrix provides improved binding capacities (>15 g/L IgA) and elution characteristics (full elution at pH 4) compared to CaptureSelect IgA Affinity Matrix.
Features of this affinity matrix include:
CaptureSelect IgA-XL Affinity Matrix binds to the Fc part of IgA. The high selectivity and yields obtained using IgA-XL Affinity Matrix enable a robust, fast, and efficient purification process with excellent purity obtained in one step.
Points forts
Animal origin statement
CaptureSelect products contain affinity ligands based on recombinant single-domain antibody fragments (VHH) created by a proprietary technology. The VHH affinity ligand is a 12–15 kDa fragment comprising the three complementarity-determining regions (CDRs) that form the antigen-binding domain, efficiently produced in the yeast Saccharomyces cerevisiae by a production process free of any animal components (animal origin-free).
Main characteristics
Matrix: agarose-based, epoxide activated
Average particle size: 65 ± 10 μm
Ligand: CaptureSelect IgA-XL affinity ligand
Ligand coupling method: epoxide
Binding capacity: > 15 g/L at 5 minutes residence time, tested with plasma-derived polyclonal IgA
Elution conditions: 20 mM sodium citrate, pH 4
Caractéristiques principales
Purification of all IgA serotypes: IgA1, IgA2, dimeric IgA, and S-IgA (secretory IgA)
IgA purification from plasma, serum, and recombinant sources
Efficient purification of IgA with high yields and retained activity
Excellent scalability
Non-animal-derived
Caractéristiques techniques
Marque
Thermo Scientific
Réf. B-LABO
BL-RE-168697
Réf. fabricant
30245090
Débit
50–200 cm/hr. (up to 2 bar)
Formule
20% (v/v) ethanol
Contenu et stockage
Store at 2–8°C. Protect from direct sunlight.
Granulométrie
65 ±10 μm
Forme
Resin Slurry
Gamme de produits
CaptureSelect™
Quantité
5 mL
À utiliser avec (application)
Purification of all IgA subtypes (IgA1, IgA2, dimeric IgA, secretory IgA)
Cible
IgA-Fc domain
Type
Affinity Matrix
Type de ligand
CaptureSelect IgA-XL Affinity Ligand
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