For the quantitative detection of Human IL-4
Interleukin-4 (IL-4) is a pleiotropic, immune-modulatory cytokine produced by activated T cells, and serves as a ligand for interleukin 4 receptor. IL-4 has been found to have the broadest range of actions. The interleukin 4 receptor also binds to IL13, which may contribute to many overlapping functions of this cytokine and IL13. STAT6, a signal transducer and activator of transcription, has been shown to play an important role in mediating the immune regulatory signal of IL-4. The IL-4 gene, IL-3, IL-5, IL-13, and CSF2 form a cytokine gene cluster on chromosome 5q. In particular, IL-4 is located in close proximity to IL13 on the chromosome. Further, the IL-4 gene, IL13 and IL5 are found to be coordinated by several long-range regulatory elements over a 120 kilobase range on the chromosome. IL-4 delta 2 is a known splice variant of IL-4.
| Marque | Invitrogen |
|---|---|
| Réf. B-LABO | BL-RE-171985 |
| Réf. fabricant | 18051673 |
| Numéro d’adhésion | P05112 |
| Plage de dosage | 0.25 to 16.0 pg/ml |
| Sensibilité du dosage | 0.1 pg/mL |
| Conjugué | HRP |
| Type de produit | ELISA |
| Type d’échantillon | Plasma |
| À utiliser avec (équipement) | Colorimetric Microplate Reader |
| Identification génétique (Entrez) | 3565 |
| Symbole de gène(s) | Il4 |
| Coefficient de variation inter-dosage | 11% |
| Coefficient de variation intra-dosage | 8.8% |
| Contenus des kits | Pre-coated 96 well plate, Standard, Sample Diluent, Assay Buffer concentrate, Biotinylated Detection Antibody, Amplification Reagent I, Amplification Reagent II, SAV-HRP, Wash Buffer, Chromogen Stop Solution Adhesive Plate Covers |
| Marqueur ou colorant | HRP |
| Quantité | 96 Tests |
| État réglementaire | RUO |
| Volume d’échantillon | 50 µL |
| Conditions de stockage | 2°C to 8°C |
| Cible | Human |
| Heure du test | 1 hr 20 min |
| Durée totale du dosage | 4 hr |
