IL-6 is a gene that encodes a cytokine that plays a role in inflammation and the maturation of B cells. The protein produced by this gene is an endogenous pyrogen that can induce fever in people with autoimmune diseases or infections. The gene is primarily expressed at sites of acute and chronic inflammation, where it is secreted into the serum and induces a transcriptional inflammatory response through interleukin 6 receptor, alpha. The functioning of this gene is implicated in a wide variety of inflammation-associated disease states, including suspectibility to diabetes mellitus and systemic juvenile rheumatoid arthritis. Elevated levels of the encoded protein have been found in virus infections, including COVID-19 (disease caused by SARS-CoV-2). Diseases associated with IL6 include Kaposi Sarcoma and Rheumatoid Arthritis, Systemic Juvenile.
- Numéro d’adhésion
- P05231
- Plage de dosage
- 0.08 to 5.0 pg/ml
- Sensibilité du dosage
- 0.03 pg/mL
- Conjugué
- HRP
- Type de produit
- ELISA
- Type d’échantillon
- Plasma
- À utiliser avec (équipement)
- Colorimetric Microplate Reader
- Identification génétique (Entrez)
- 3569
- Symbole de gène(s)
- Il6
- Coefficient de variation inter-dosage
- 6%
- Coefficient de variation intra-dosage
- 4.9%
- Contenus des kits
- Pre-coated 96 well plate, Standard, Sample Diluent, Assay Buffer concentrate, Biotinylated Detection Antibody, Amplification Reagent I, Amplification Reagent II, SAV-HRP, Controls, Wash Buffer, Chromogen Stop Solution Adhesive Plate Covers
- Marqueur ou colorant
- HRP
- Quantité
- 96 Tests
- État réglementaire
- RUO
- Volume d’échantillon
- 50 µL
- Conditions de stockage
- 2°C to 8°C
- Cible
- Human
- Heure du test
- 1 hr 20 min
- Durée totale du dosage
- 4 hr
