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Thermo Scientific™ CaptureSelect™ CH1-XL Mag… | B-LABO France
Thermo Scientific™ CaptureSelect™ CH1-XL Magnetic Agarose Beads
Réf. : BL-RE-175262Réf. fabricant : 30275933 1 mL
469,00 € HT
Thermo Scientific™ CaptureSelect™ CH1-XL Magnetic Agarose Beads are high-capacity, high-throughput magnetic affinity particles for antibody purification using manual or robotic magnetic separators.
Capacité de liaison
>4 mg IgG/mL slurry
Matrice
6% cross-linked magnetized agarose
Granulométrie
25 to 30 μm
Forme
Pâte de résine
Gamme de produits
CaptureSelect™
Marque
Thermo Scientific
CaptureSelect CH1-XL Magnetic Agarose Beads are high-capacity, high-throughput magnetic affinity particles for antibody purification using manual or robotic magnetic separators. The CaptureSelect CH1-XL affinity ligand recognizes the CH1 domain of human IgG, enabling purification of all subclasses (1, 2, 3, and 4) of human IgG and Fab fragments, independent of the light-chain isotype and source material. Due to selectivity for the CH1 domain, no co-purification of free light chains will occur. IgG and Fab fragments can be directly isolated from complex source materials in a single step with high purity and yield.
Features of CaptureSelect CH1-XL Magnetic Agarose Beads include:
Points forts
Free of animal components
CaptureSelect products contain affinity ligands based on recombinant single-domain antibody fragments (VHH) created by a proprietary technology. The VHH affinity ligand is a 12 to 15 kDa fragment comprising the three complementarity-determining regions (CDRs) that form the antigen-binding domain, efficiently produced in the yeast Saccharomyces cerevisiae by a production process free of any animal components (Animal Origin-Free).
Main characteristics
Matrix: 6% cross-linked magnetized agarose
Average particle size: 25–30 μm
Suspension: 25% slurry
Ligand: CaptureSelect CH1-XL affinity ligand
Binding capacity: >4 mg IgG/mL slurry
Elution conditions: 50 mM sodium acetate, pH 4.0/0.1 M glycine, pH 3.0
Caractéristiques principales
One-step human IgG purification with high purity, from crude material
Compatible with manual and automated workflows (e.g., Thermo Scientific KingFisher instruments)
Short operation time
Mild elution at pH 4
No sample dilution required during isolation, repetitive sample loading feasible
No binding to bovine antibodies, allowing use of fetal bovine serum in the sample material
Non-animal-derived
Caractéristiques techniques
Marque
Thermo Scientific
Réf. B-LABO
BL-RE-175262
Réf. fabricant
30275933
Capacité de liaison
>4 mg IgG/mL slurry
Matrice
6% cross-linked magnetized agarose
Granulométrie
25 to 30 μm
Forme
Pâte de résine
Gamme de produits
CaptureSelect™
Quantité
1 mL
Type
Magnetic Agarose Bead
Type de ligand
CH1-XL affinity ligand
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