Thermo Scientific™ Dynabeads™ CaptureSelect™ AAV9 Magnetic Beads

Ref: p-200004746
456.00€ - 8040.00€

Thermo Scientific™ Dynabeads™ CaptureSelect™ AAV9 Magnetic Beads are high-capacity, high-throughput magnetic affinity particles for the purification of naturally occurring and synthetic adeno-associated virus serotype 9 (AAV9) used for gene therapy applications.

Capacité de liaison:
&gt;0.5 x 10<sup>11</sup> vp/mg beads
Concentration:
30 mg beads/mL slurry, 1 mg contains approximately 1.3 x 10<sup>7</sup> beads
Formule:
4 to 6% (v/v) Slurry
Matrice:
Non-porous monodisperse superparamagnetic beads
Granulométrie:
4.5 &mu;m
Gamme de produits:
CaptureSelect&trade;
Brand
Thermo Scientific&trade;
Référence Prix Marque Capacité Quantité Add to cart
30276152 456.00€ - 8040.00€ Thermo Scientific™ 50 mL 50 mL
30276138 456.00€ - 8040.00€ Thermo Scientific™ 5 mL 5 mL
30275957 456.00€ - 8040.00€ Thermo Scientific™ 1 mL 1 mL

Dynabeads CaptureSelect AAV9 Magnetic Beads are high-capacity, high-throughput magnetic affinity particles for the purification of naturally occurring and synthetic adeno-associated virus serotype 9 (AAV9) used for gene therapy applications. The anti-AAV9 affinity ligand demonstrates good binding reactivity towards the AAV9 serotype. The magnetic beads enable purification using manual and robotic magnetic separators of the AAV9 serotype directly from crude feedstock in a single step with high purity and yield.

Features of DynaBeads CaptureSelect AAV9 Magnetic Beads include:

  • One-magnetic-step AAV purification from crude material with high purity and yield
  • Compatible with manual and automated workflows
  • High specificity and capacity
  • Easy upscaling to higher volumes
  • Non-animal derived

The magnetic beads bind with high affinity specifically to the AAV9 serotype. For the isolation of other AAV serotype capsids we recommend DynaBeads CaptureSelect AAVX magnetic beads (Cat. No. 2853522001, 2853522005, 2853522050).

Animal origin statement

CaptureSelect products contain affinity ligands based on recombinant single-domain antibody fragments (VHH) created by a proprietary technology. The VHH affinity ligand is a ∼12–15 kDa fragment comprising the three complementarity-determining regions (CDRs) that form the antigen-binding domain. The ligand is efficiently produced in yeast Saccharomyces cerevisiae by a production process free of any animal components (Animal Origin-Free).

Main characteristics

  • Bead matrix: non-porous monodisperse superparamagnetic beads
  • Bead size: 4.5 μm
  • Ligand: CaptureSelect AAV9 affinity ligand
  • Binding capacity: >5 x 1011 viral particles/mg beads
  • Elution conditions: 50 mM citric acid, pH 2.5–3.0
  • Formulation buffer: tris-buffered saline, 0.05% Tween 20, 0.05 % sodium azide

Capacité de liaison : >0.5 x 1011 vp/mg beads

Concentration : 30 mg beads/mL slurry, 1 mg contains approximately 1.3 x 107 beads

Formule : 4 to 6% (v/v) Slurry

Matrice : Non-porous monodisperse superparamagnetic beads

Granulométrie : 4.5 μm

Gamme de produits : CaptureSelect™

À utiliser avec (application) : Magnetic isolation of AAV9 capsids

Cible : AAV9 (Adeno-associated serotype 9)

Type de ligand : CaptureSelect™ AAV9 Affinity Ligand

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