CaptureSelect CH1-XL GoPure Columns are ready-to-use columns designed for fast and easy purification of human IgG on standard chromatography systems with high purity and yield in a single step.
Volume du lit
5 mL
Capacité (métrique)
5 mL column
Matrice
CH1-XL Affinity Matrix
Contenu et stockage
Store at 2°C to 8°C. Protect from direct daylight.
Diamètre (métrique)
16 mm
Marque
Thermo Scientific
The pre-packed column contains CaptureSelect CH1-XL Affinity Matrix, which recognizes the CH1 domain of human IgG antibodies, enabling purification of all subclasses (1, 2, 3, and 4) of human IgG and Fab fragments, independent of the light-chain isotype and source material.
Features of this affinity matrix include:
Points forts
Free of animal components
CaptureSelect products contain affinity ligands based on recombinant single-domain antibody fragments (VHH) created using a proprietary technology. The VHH affinity ligand is a 12 to 15 kDa fragment comprising the three complementarity-determining regions (CDRs) that form the antigen-binding domain, efficiently produced in the yeast Saccharomyces cerevisiae by a production process free of any animal components (Animal Origin-Free).
Main characteristics
Matrix: agarose-based, epoxide-activated
Average particle size: 65 ± 10 μm
Caractéristiques principales
Platform approach for purification of IgGs and their Fab fragments directly from complex source materials in a single step with high purity and yield
Elution possible at pH 4.0–4.5 with 50 mM acetate buffer
No co-purification of overproduced free light chains or light chain dimers
Specific for human antibodies; works in the presence of serum (bovine/horse)
Non-animal-derived
Caractéristiques techniques
Marque
Thermo Scientific
Réf. B-LABO
BL-RE-175287
Réf. fabricant
30275601
Volume du lit
5 mL
Capacité (métrique)
5 mL column
Matrice
CH1-XL Affinity Matrix
Contenu et stockage
Store at 2°C to 8°C. Protect from direct daylight.
Diamètre (métrique)
16 mm
Pression de fonctionnement max.
0.3 Mpa
Granulométrie
63 μm
Forme
Agarose Bead
Gamme de produits
CaptureSelect™
Quantité
5 mL
Type
Pre-packed Column
Hauteur du lit
25 mm
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